We respectfully report that our manuscript “Cell proteomic footprint” was published as a research article in journal “Rapid Communications in Mass Spectrometry”. 
       
         Cell cultures have a great commercial value in a wide range of therapeutic applications, among these are: tissue engineering applications, regenerative medicine, cell-based anti-cancer vaccination, etc. However, cultivated cells indicate that cross-contamination between cell lines is widely prevalent, and continues to be a major problem. From the known cell authentication methods, short tandem repeat profiling (DNA fingerprinting) is considered to be the most powerful method that provides an international reference standard for authentication of human cell lines. However, DNA fingerprinting is usually so complex and labor intensive that the cost of fingerprinting can be up to $200 for each cell line. Thus, the control of cell propagation by DNA fingerprinting, when following a GTP (Good Tissue Practice) protocol, may increase the cost of end-product substantially.
        Biotechnology firm “BioBohemia”, which has a wide practice with cell cultures and keeping cell collection, in collaboration with firm “Bruker”, which is the performance leader in life-science and analytical systems, report a simple and straightforward approach (cell culture footprinting) for authentication of biological cells and their subpopulations with high speed (10 min), low sample cost (15$), and high sensitivity (500 cells are enough). Moreover, proposed approach can be easily integrated in cell cultivation technology. Cell culture footprinting offers an excellent alternative to traditional laboratory authentication methods of cells and monitoring cell identity during propagation in a laboratory.

We thank you for your interest to our work.

 

BioBohemia